Introduction
Brand name: Telget‑CL 40/10
Manufacturer: Astemax Biotech
Composition: Telmisartan 40 mg + Cilnidipine 10 mg tablet
Telget‑CL 40/10 is a fixed‑dose dual antihypertensive combination designed for essential hypertension where monotherapy provides inadequate control.
Key ingredients and mechanism
Telmisartan 40 mg
An angiotensin‑II receptor blocker (ARB) that blocks AT1 receptors, preventing vasoconstriction and aldosterone release, thereby lowering blood pressure and offering organ‑protective effects.
Cilnidipine 10 mg
A dual‑channel L/N‑type calcium channel blocker that dilates both arterial and venous resistance vessels, improving peripheral blood flow and reducing afterload with a lower tendency to cause pedal oedema compared with classic L‑type CCBs.
Main indications
Uncontrolled or moderate‑to‑severe essential hypertension, especially in patients needing dual‑mechanism BP control.
Hypertensive patients with diabetes, early renal involvement, or metabolic syndrome where the combination helps BP, improves vascular function, and may favourably influence insulin sensitivity and micro‑vascular parameters.
Typical use and precautions
Usual dose is 1 tablet (Telmisartan 40 mg + Cilnidipine 10 mg) once daily, usually in the morning, with or without food; strength and dosing can be adjusted for renal/hypotension‑prone patients under medical supervision.
