Introduction
Pregasoft N is Astemax Biotech’s branded tablet combining Pregabalin (typically 75 mg) and Nortriptyline (10 mg), designed for comprehensive neuropathic pain management.
Key Ingredients
Pregabalin binds to alpha-2-delta subunits of voltage-gated calcium channels, reducing excitatory neurotransmitter release to calm overactive nerves. Nortriptyline, a tricyclic antidepressant, increases serotonin and noradrenaline levels to block pain signal transmission in the brain and spinal cord.
Health Benefits
Effectively relieves diabetic neuropathy, post-herpetic neuralgia, fibromyalgia, chronic back/neck pain, and nerve injury pain by addressing both peripheral sensitization and central pain processing. The combination provides superior relief (60-80% pain reduction) compared to monotherapy, improving sleep and daily function













