Introduction
Giusep S375 is Astemax Biotech’s branded Ceftriaxone 250 mg + Sulbactam 125 mg injection (375 mg total strength), designed for treating resistant bacterial infections.
Key Ingredients
Ceftriaxone (250 mg), a third-generation cephalosporin, kills bacteria by disrupting cell wall synthesis. Sulbactam (125 mg) inhibits beta-lactamase enzymes, extending ceftriaxone’s effectiveness against resistant strains.
Health Benefits
Effectively manages respiratory infections, UTIs, skin/soft tissue infections, intra-abdominal infections, and surgical prophylaxis, achieving higher success rates (85-95%) against beta-lactamase producing pathogens compared to ceftriaxone alone.
Recommended Dosage
Administer 375 mg (1 vial) IV/IM every 12 hours for adults; reconstitute with 5 ml water for injection (IV) or 2 ml 1% lidocaine (IM); infuse over 5-10 minutes; course typically 5-14 days.
Usage Precautions
For hospital use only; monitor for diarrhea, rash, or allergy. Avoid in cephalosporin hypersensitivity or neonates; adjust dose in renal impairment
