Introduction
Brand name: ST‑PRED 16 mg
Composition: Methylprednisolone 16 mg tablet
What it is
ST‑PRED 16 mg is a systemic corticosteroid tablet containing methylprednisolone 16 mg, a synthetic glucocorticoid with potent anti‑inflammatory and immunosuppressive effects. It is used for a variety of inflammatory and immune‑mediated conditions across multiple organ systems.
Main indications
Rheumatologic and musculoskeletal disorders: Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, acute gout, polymyalgia rheumatica, and other inflammatory joint diseases.
Allergic and dermatologic conditions: Severe allergic reactions, asthma exacerbations, atopic dermatitis, psoriasis, and other severe inflammatory skin diseases.
Respiratory, ocular, and other inflammatory states:
Severe bronchospasm and COPD exacerbations.
Inflammatory eye diseases (posterior‑segment uveitis) and severe inflammatory bowel disease (e.g., IBD flares).
Immunosuppressive therapy: Certain autoimmune diseases, nephrotic syndrome, and as part of oncologic regimens.
How it works
Methylprednisolone binds to intracellular glucocorticoid receptors, modulating gene expression to:
Suppress multiple inflammatory mediators (cytokines, prostaglandins, leukotrienes).
Decrease leukocyte migration and activation, reducing swelling, redness, heat, and pain.
