Introduction
Brand name: Astovestin AV
Manufacturer: Astemax Biotech
Composition: Aspirin (gastro‑resistant) 75 mg + Atorvastatin 40 mg capsule
Astovestin AV is a dual‑action cardioprotective fixed‑dose combination that merges low‑dose aspirin (enteric‑coated/gastro‑resistant) with atorvastatin 40 mg in a single capsule. It is designed for secondary prevention and high‑risk primary prevention of cardiovascular events such as heart attack, stroke, and atherosclerotic cardiovascular disease.
Key pharmacology
Aspirin 75 mg (gastro‑resistant)
A low‑dose antiplatelet that irreversibly inhibits COX‑1, reducing thromboxane‑A₂‑mediated platelet aggregation and arterial clot formation.
Gastro‑resistant coating helps minimise gastric irritation and ulcer risk while maintaining efficacy.
Atorvastatin 40 mg
A high‑intensity statin that inhibits HMG‑CoA reductase, lowering LDL‑cholesterol, total cholesterol, and triglycerides and stabilising atherosclerotic plaque.
Typical use and precautions
Usual dose: 1 capsule (Aspirin 75 mg + Atorvastatin 40 mg) once daily, usually in the evening, under physician supervision
Astovestin AV can be positioned as a WHO‑GMP‑oriented, physician‑recommended secondary‑prevention capsule for cardiology and diabetology‑focused prescribers managing patients requiring long‑term lipid‑plus‑antiplatelet therapy.
